A comparative genome study and squid embryo experiment explore how folded DNA may shape cephalopod gene regulation.

A massive Hi-C study across eight mouse strains shows that the strength of chromatin boundary insulation predicts how faithfully topologically associating domains are conserved across mammalian ...

Chromatin loops, which are formed by CTCF and cohesin, mediate precise long-range gene regulation by connecting enhancers with their target promoters. During aging and cellular senescence, these loops ...

A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also ...

Inside each human cell, about 2 meters (6.6 feet) of genomic DNA must be accurately copied and equally transmitted to two daughter cells during cell division. To achieve this, the copied DNA is ...

Chinese researchers have developed a groundbreaking technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.