Every cell type in the human body carries the same approximately 3.2 billion base pairs of DNA, yet a liver cell behaves nothing like a neuron. The epigenome explains this difference: in each cell, ...

DNA methylation and epigenetic modifications play pivotal roles in the initiation and progression of esophageal cancer, encompassing both squamous cell carcinoma and adenocarcinoma. Methyl groups ...

Cardiovascular disease remains the leading cause of mortality worldwide, necessitating deeper insights into its molecular underpinnings beyond genetic predisposition. Epigenetic modifications, ...

A new review in Cellular and Molecular Life Sciences maps how the epigenome of the postnatal male germline balances the ...

It's just my genes, so I can't help it' is outdated! You can start designing your future self today.'My parents age easily, ...

From Gene Expression Regulation to Understanding PathophysiologyIntroductionWhile genetic factors contribute strongly to the ...

A new review maps how common genetic variants, insertion/deletion polymorphisms, microRNAs, DNA methylation and histone ...

A research team from AIST, the Institute of Science Tokyo, and Ritsumeikan University has demonstrated that the phase behavior of histone–DNA condensates depends on the site of histone acetylation.

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...